Publications- SiDMAP

Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow towards nucleic acid and fatty acid synthesis in myeloid tumor cells

Boren, J., Cascante, M., Marin, S., Comín-Anduix, B., Centelles, J.J., Lim, S., Bassilian, S., Ahmed, S., Lee W-N.P., Boros, L.G. Journal of Biological Chemistry 276: 37747-37753, 2001

Imatinib and chronic-phase leukemias.

Boros, L.G., Lee, W-N.P., Cascante, M. New England Journal of Medicine 347: 67-68, 2002.

Metabolic control analysis in drug discovery and disease

Cascante, M., Boros, L.G., Comin, B., Atauri, P., Centelles, J.J., Lee, W-N.P. Nature Biotechnology 20: 246-249, 2002.

Metabolic Profiling of Cell Growth and Death in Cancer: applications in drug discovery

Boros, L.G., Cascante, M., Lee, W-N.P. Drug Discovery Today 7: 364-372, 2002.

Loss of regulation of lipogenesis in the Zucker diabetic rat. II. Changes in stearate and oleate synthesis

Bassilian, S., Ahmed, S., Lim, S.K., Boros, L.G., Mao, C.S., Lee, W-N.P. American Journal of Physiology Endocrinology & Metabolism 282: E507-13, 2002.

A metabolic hypothesis of cell growth and death in pancreatic cancer

Boros, L.G., Lee, W-N.P., Go, V.L.W. Pancreas 24: 26-33, 2002.

The stable isotope-based dynamic metabolic profile of butyrate induced HT29 cell differentiation

Boren, J., Lee, W.N., Bassilian, S., Centelles, J.J., Lim, S., Ahmed, S., Boros, L.G., Cascante, M. Journal of Biological Chemistry 278: 28395-28402, 2003.

Use of metabolic pathway flux information in targeted cancer drug design

Laszlo G. Boros, Natalie J. Serkova, Marta S. Cascante, Wai-Nang Paul Lee Download .pdf

Metabolic Profiling of Cell Growth and Death in Cancer: applications in drug discovery

Boros, L.G., Cascante, M., Lee, W-N.P. Metabolic Profiling of Cell Growth and Death in Cancer: applications in drug discovery. Drug Discovery Today 7: 364-372, 2002.

Metabolic control analysis in drug discovery and disease

Cascante, M., Boros, L.G., Comin, B., Atauri, P., Centelles, J.J., Lee, W-N.P. Metabolic control analysis in drug discovery and disease.Nature Biotechnology 20: 246-249, 2002.

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